[BAKER DONELSON BEARMAN, CALDWELL & BERKOWITZ, PC LETTERHEAD]



                                October 14, 2005


VIA OVERNIGHT DELIVERY
- ----------------------

United States Securities and Exchange Commission
Division of Corporation Finance
450 Fifth Street, N.W.
Washington, D.C. 20549
Attention: Michael McTiernan, Staff Attorney

Ladies and Gentlemen:

On behalf of Medical Properties Trust, Inc. (the "Company"), and pursuant to
our discussion this afternoon, enclosed herewith is a memorandum from Goodwin
Proctor LLP, as counsel to Wellington Management Company, LLP, relating to
certain selling stockholders named in Amendment No. 3 to the Company's
Registration Statement on Form S-11 (the "Amendment"), as filed with the
Securities and Exchange Commission on October 13, 2005, File No. 333-121883
(the "Registration Statement"). Please do not hesitate to contact the
undersigned or, in her absence, Thomas O. Kolb at (205) 250-8321, if you have
any questions or comments relating to this correspondence.



                                   Very truly yours,

                                   /s/ Irene Graves
                                   -----------------
                                   Irene Graves


Enclosure

cc: Medical Properties Trust, Inc.
    Wellington Management Company, LLP





                                  [Letterhead]

                                                [Goodwin Proctor LLP LETTERHEAD]
MEMORANDUM



To      Julie A. Jenkins
        Gina M. DiMento
                Wellington Management Company, LLP

From    Thomas J. LaFond

Date    October 13, 2005


We have prepared this memorandum at your request in connection with the
review by the staff of the Securities and Exchange Commission ("SEC") of the
registration statement on Form S-l1 (the "Registration Statement") of Medical
Properties Trust (the "Registrant"). Certain investment advisory client accounts
("Client Accounts") advised by Wellington Management Company, LLP ("Wellington")
are named as selling shareholders in the Registration Statement. The
Registration Statement discloses the names of the Client Accounts and the fact
that Wellington is the investment adviser to the Client Accounts.

We understand from discussions with counsel to the Registrant that, in the
course of reviewing the Registration Statement, the SEC staff has orally
requested a written explanation of the legal basis as to why the Registrant is
not required to include, in the list of selling shareholders contained in the
Registration Statement, the names of the natural persons with power to vote or
to dispose of the securities offered for resale by the Client Accounts.

For the reasons set forth below, we do not believe that the requested disclosure
is required under applicable law.

APPLICABLE LAW

Form S-l1 requires, among other things, disclosure of the matters covered by
Regulation S-K, Item 507. Item 507 provides: "If security holders of a small
business issuer are offering securities, name each selling security holder,
state any position, office, or other material relationship which the selling
security holder has had within the past three years with the small business
issuer or any of its predecessors or affiliates, and state the amount of
securities of the class owned by such security holder before the offering, the
amount to be offered for the security holder's account, the amount and (if one
percent or more) the percentage of the class to be owned by such security holder
after the offering is complete."

Interpretation 4S of the Regulation S-K portion of the March 1999 supplement to
the CF telephone interpretation manual (the "1999 Interpretation") provides: "We
were asked whether identification of an




entity as a selling shareholder in the registration statement must include
disclosure of the persons who have sole or shared voting or investment power
over the entity. The company must identify in the registration statement the
person or persons who have voting or investment control over the company's
securities that the entity owns. Use Rule 13d-3 by analogy to make the
determination."

The SEC's 1997 telephone interpretation 60 (Regulation S-K) provides: "The term
"security holder", as used in Item 507 of Regulation S-K, means beneficial
holders, not nominee holders or other such holders of record."

ANALYSIS

On the basis of the above, it is our view that the selling shareholder
disclosure required by Item 507 of Regulation S-K should be disclosure of the
"beneficial owners" of the shares being sold and, accordingly, should be
consistent with what the selling shareholders would report under Section 13 of
the Securities Exchange Act of 1934 and Rule 13d-l thereunder if the selling
shareholders were subject to such reporting requirements. The appropriate filing
form under Section 13 for a registered investment adviser such as Wellington is
generally Schedule 13G. Schedule 13G does not require disclosure of natural
persons having the power to vote or dispose of the securities beneficially owned
by an investment adviser. Accordingly, based on and subject to the foregoing, we
do not believe Regulation S-K, Item 507 or the SEC staff's interpretations
thereof require additional disclosure with respect to Wellington or the Client
Accounts in the Registration Statement.

This result is consistent with the applicable rules and with the underlying
purpose of the disclosure requirements. As we understand it, the suggestion has
been made that the 1999 Interpretation requires Wellington (along with all other
investment advisers) to disclose the names of specific portfolio managers, proxy
voting officers, and similar officers who carry out investment and voting
decisions on a day-to-day basis with respect to portfolio securities owned by
investment advisory client accounts. Such a reading of that interpretation would
require disclosure that is, in our view, not meaningful, and that would be
inconsistent with the underlying purpose of the disclosure requirements, which
is to ensure that investors know the identity of beneficial owners of shares and
to prevent the use of nominees or mere record shareholders to shield the
identity of beneficial owners. There is clearly no such intention or effect
here: the Client Accounts own the subject shares, and are advised by Wellington,
all as disclosed in the Registration Statement.

You may share this memorandum with counsel for the Registrant for the sole
purpose of providing it to the SEC staff in connection with the resolution of
the matters described above. Please do not hesitate to give me a call at the
above number if you would like to discuss this analysis or if we can be of
further assistance.


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