Exhibit 99.1

MEDICAL PROPERTIES TRUST, INC. REPORTS FIRST QUARTER RESULTS

First Quarter Per Share Net Income of $0.15 and Normalized FFO of $0.37

Completes $2.0 Billion Circle/BMI Acquisition Marking the Largest Transaction in Company’s History;

$1.8 Billion in Liquidity with No Near-Term Debt Maturities; Collected 96% of April Rent

Birmingham, AL – April  29, 2020 – Medical Properties Trust, Inc. (the “Company” or “MPT”) (NYSE: MPW) today announced financial and operating results for the first quarter ended March 31, 2020 and recent highlights.

“MPT’s U.S. and international operators are playing crucially important roles in the global fight against COVID-19, and we are extraordinarily grateful for the work their employees are doing on the frontlines to care for patients,” said Edward K. Aldag, Jr., MPT’s Chairman, President and Chief Executive Officer. “Our tenants represent some of the best capitalized and most profitable operators in the hospital industry – in the U.S. and globally. We are in constant contact with our largest operators during this pandemic, and based on the financial information they have provided us, we and they feel good about our continued receipt of rental payments. In April we received 96% of total rent and expect that trend to continue. ”

Mr. Aldag continued, “MPT is in a strong position with approximately $500 million of cash and an undrawn $1.3 billion revolving credit facility. We entered the first quarter by completing our largest single transaction to date, the $2.0 billion acquisition of 30 UK hospitals in early January. Before the pandemic, we were working on a tremendous set of opportunities that we expected to complete in 2020. Today, not only do we continue to see those opportunities, albeit possibly delayed somewhat, but we have been presented with a number of additional promising opportunities. We remain very bullish on both near and longer-term opportunities for MPT to continue executing its highly accretive acquisition strategies.”

FIRST QUARTER AND RECENT HIGHLIGHTS

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Included in the financial tables accompanying this press release is information about the Company’s assets and liabilities, net income and reconciliations of net income to NFFO, all on a basis comparable to 2019 results, and a reconciliation of pro forma total gross assets to total assets.

PORTFOLIO UPDATE

MPT completed the acquisition of the 30-hospital BMI transaction and commenced recognition of rental income in early January based on the pre-acquisition lease terms. Upon the U.K.’s Competition and Markets Authority’s recent approval of the post-acquisition lease terms, including a higher GAAP lease rate, MPT will begin recognizing rental income at the new rate; had this higher rate been effective for the entirety of the first quarter, NFFO would have been higher by approximately $0.024 per diluted share.

In response to conditions created by the pandemic, MPT has offered to donate to a local municipality the real estate related to a general acute care hospital that was closed by the operator/lessee during 2019. The carrying amount of this real estate was approximately $9.1 million, which is reflected in first quarter net income as an impairment charge.

The Company has pro forma total gross assets of approximately $16.5 billion, including $13.3 billion in general acute care hospitals, $1.8 billion in inpatient rehabilitation hospitals, and $0.3 billion in long-term acute care hospitals. The pro forma portfolio includes 389 properties representing more than 41,000 licensed beds in 34 states and in Germany, the United Kingdom, Switzerland, Italy, Spain, Portugal and Australia. The properties are leased to or mortgaged by 41 hospital operating companies.

OPERATING RESULTS AND OUTLOOK

Net income for the first quarter of 2020 was $81.0 million (or $0.15 per diluted share), compared to $75.8 million ($0.20 per diluted share) in the first quarter of 2019.

NFFO for the first quarter of 2020 was $191.2 million (or $0.37 per diluted share), compared to $117.8 million ($0.31 per diluted share) in the first quarter of 2019.

The Company reaffirms its estimated annualized NFFO run rate range including $1.14 to $1.17 per diluted share for net income and $1.65 to $1.68 per diluted share for NFFO based on all announced transactions and an assumed capital structure that results in a net debt to EBITDA ratio of approximately 5.5 times.

These estimates do not include the effects, if any, of unexpected real estate operating costs, changes in accounting pronouncements, litigation costs, debt refinancing costs, acquisition costs, currency exchange rate movements, interest rate hedging activities, write-offs of straight-line rent or other non-recurring or unplanned transactions. Moreover, these estimates do not provide for the impact on MPT or its tenants and borrowers or on local and national governments worldwide of the ongoing global COVID-19 pandemic. These estimates may change if the Company acquires or sells assets in amounts that are different from estimates,

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market interest rates change, debt is refinanced, new shares are issued, additional debt is incurred, other operating expenses vary, income from our equity investments vary from expectations, or existing leases do not perform in accordance with their terms.

CONFERENCE CALL AND WEBCAST

The Company has scheduled a conference call and webcast for Thursday, April 30, 2020 at 11:00 a.m. Eastern Time to present the Company’s financial and operating results for the quarter ended March 31, 2020. The dial-in numbers for the conference call are 844-535-3969 (U.S. and Canada) and 409-937-8903 (International); both numbers require passcode 7887848. The conference call will also be available via webcast in the Investor Relations section of the Company’s website, www.medicalpropertiestrust.com .

A telephone and webcast replay of the call will be available beginning shortly after the call’s completion through May 14, 2020. Dial-in numbers for the replay are 855-859-2056 and 404-537-3406 for U.S./Canada and International callers, respectively. The replay passcode for all callers is 7887848.

The Company’s supplemental information package for the current period will also be available on the Company’s website in the Investor Relations section.

About Medical Properties Trust, Inc.

Medical Properties Trust, Inc. is a self-advised real estate investment trust formed in 2003 to acquire and develop net-leased hospital facilities. From its inception in Birmingham, Alabama, the Company has grown to become one of the world’s largest owners of hospitals with 389 facilities and more than 41,000 licensed beds in eight countries and across three continents. MPT’s financing model facilitates acquisitions and recapitalizations and allows operators of hospitals to unlock the value of their real estate assets to fund facility improvements, technology upgrades and other investments in operations. For more information, please visit the Company’s website at www.medicalpropertiestrust.com .

This press release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements can generally be identified by the use of forward-looking words such as “may”, “will”, “would”, “could”, “expect”, “intend”, “plan”, “estimate”, “target”, “anticipate”, “believe”, “objectives”, “outlook”, “guidance” or other similar words, and include statements regarding our strategies, objectives, future expansion and development activities, and expected financial performance. Forward-looking statements involve known and unknown risks and uncertainties that may cause our actual results or future events to differ materially from those expressed in or underlying such forward-looking statements, including, but not limited to: (i) the economic, political and social impact of, and uncertainty relating to, the COVID-19 pandemic, including governmental assistance to hospitals and healthcare providers, including certain of our tenants; (ii) the ability of our tenants, operators and borrowers to satisfy their obligations under their respective contractual arrangements with us, especially as a result of the adverse economic impact of the COVID-19 pandemic, and government regulation of hospitals and healthcare providers in connection with same, such as mandatory deferrals of non-critical surgeries and intake of COVID-19 patients (as further detailed in our Current Report on Form 8-K filed with the SEC on April 8, 2020); (iii) our expectations regarding annual run-rate net income and NFFO per share; (iv) our success in implementing our business strategy and our ability to identify, underwrite, finance, consummate and integrate acquisitions and investments; (v) the nature and extent of our current and future competition; (vi) macroeconomic conditions, such as a disruption of or lack of access to the capital markets; (vii) our ability to obtain debt financing on attractive terms or at all, which may adversely impact our ability to pursue acquisition and development opportunities and pay down, refinance, restructure or extend our indebtedness as it becomes due; (viii) increases in our borrowing costs as a result of changes in interest rates and other factors, including the potential phasing out of LIBOR after 2021; (ix) international, national and local economic, real estate and other market conditions, which may negatively impact, among other things, the

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financial condition of our tenants, lenders and institutions that hold our cash balances, and may expose us to increased risks of default by these parties; (x) factors affecting the real estate industry generally or the healthcare real estate industry in particular; (xi) our ability to maintain our status as a REIT for federal and state income tax purposes; (xii) federal and state healthcare and other regulatory requirements, as well as those in the foreign jurisdictions where we own properties; (xiii) the value of our real estate assets, which may limit our ability to dispose of assets at attractive prices or obtain or maintain equity or debt financing secured by our properties or on an unsecured basis; (xiv) the ability of our tenants and operators to comply with applicable laws, rules and regulations in the operation of the our properties, to deliver high-quality services, to attract and retain qualified personnel and to attract residents and patients; and (xv) potential environmental contingencies and other liabilities.

The risks described above are not exhaustive and additional factors could adversely affect our business and financial performance, including the risk factors discussed under the section captioned “Risk Factors” in our Annual Report on Form 10-K for the year ended December 31, 2019. Forward-looking statements are inherently uncertain and actual performance or outcomes may vary materially from any forward-looking statements and the assumptions on which those statements are based. Readers are cautioned to not place undue reliance on forward-looking statements as predictions of future events. We disclaim any responsibility to update such forward-looking statements, which speak only as of the date on which they were made.

# # #

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MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES

Consolidated Balance Sheets

MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES

Consolidated Statements of Income

(Unaudited)

MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES

Reconciliation of Net Income to Funds From Operations

(Unaudited)

Notes:

In addition to presenting FFO in accordance with the NAREIT definition, we also disclose normalized FFO, which adjusts FFO for items that relate to unanticipated or non-core events or activities or accounting changes that, if not noted, would make comparison to prior period results and market expectations less meaningful to investors and analysts. We believe that the use of FFO, combined with the required GAAP presentations, improves the understanding of our operating results among investors and the use of normalized FFO makes comparisons of our operating results with prior periods and other companies more meaningful. While FFO and normalized FFO are relevant and widely used supplemental measures of operating and financial performance of REITs, they should not be viewed as a substitute measure of our operating performance since the measures do not reflect either depreciation and amortization costs or the level of capital expenditures and leasing costs necessary to maintain the operating performance of our properties, which can be significant economic costs that could materially impact our results of operations. FFO and normalized FFO should not be considered an alternative to net income (loss) (computed in accordance with GAAP) as indicators of our results of operations or to cash flow from operating activities (computed in accordance with GAAP) as an indicator of our liquidity.

We calculate adjusted funds from operations, or AFFO, by subtracting from or adding to normalized FFO (i) non-cash revenue, (ii) non-cash share-based compensation expense, and (iii) amortization of deferred financing costs. AFFO is an operating measurement that we use to analyze our results of operations based on the receipt, rather than the accrual, of our rental revenue and on certain other adjustments. We believe that this is an important measurement because our leases generally have significant contractual escalations of base rents and therefore result in recognition of rental income that is not collected until future periods, and costs that are deferred or are non-cash charges. Our calculation of AFFO may not be comparable to AFFO or similarly titled measures reported by other REITs. AFFO should not be considered as an alternative to net income (calculated pursuant to GAAP) as an indicator of our results of operations or to cash flow from operating activities (calculated pursuant to GAAP) as an indicator of our liquidity.

MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES

Annual Run-Rate Guidance Reconciliation

(Unaudited)

Pro Forma Total Gross Assets

(Unaudited)

Exhibit 99.2

Medical Properties Trust Supplemental Information FIRST QUARTER 2020

COMPANY OVERVIEW Company Information 3 FINANCIAL INFORMATION Reconciliation of Net Income to Funds from Operations 5 Debt Summary 6 Debt Maturity Schedule 7 Pro Forma Net Debt /Annualized Adjusted EBITDA 8 PORTFOLIO INFORMATION Lease and Loan Maturity Schedule 9 Total Pro Forma Gross Assets and Actual Revenue by Asset Type, Operator, State and Country 10 EBITDARM to Rent Coverage 13 Summary of Acquisitions and Development Projects 14 FINANCIAL STATEMENTS Consolidated Statements of Income 15 Consolidated Balance Sheets 16 Unconsolidated Joint Venture Investments 17 TABLE OF CONTENTS FORWARD-LOOKING STATEMENT Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results of the Company or future events to differ materially from those expressed in or underlying such forward-looking statements, including without limitation: Normalized FFO per share; expected payout ratio, the amount of acquisitions of healthcare real estate, if any; estimated debt metrics, portfolio diversification, capital markets conditions, the repayment of debt arrangements; statements concerning the additional income to the Company as a result of ownership interests in certain hospital operations and the timing of such income; the payment of future dividends, if any; completion of additional debt arrangement, and additional investments; national and international economic, business, real estate and other market conditions; the competitive environment in which the Company operates; the execution of the Company’s business plan; financing risks; the Company’s ability to maintain its status as a REIT for federal income tax purposes; acquisition and development risks; potential environmental and other liabilities; potential impact from COVID-19 on our tenants/borrowers and the related impact to us; and other factors affecting the real estate industry generally or healthcare real estate in particular. For further discussion of the factors that could affect outcomes, please refer to the “Risk Factors” section of the Company’s Annual Report on Form 10-K for the year ended December 31, 2019, and as updated by the Company’s subsequently filed Quarterly Reports on Form 10-Q and other SEC filings. Except as otherwise required by the federal securities laws, the Company undertakes no obligation to update the information in this report. Certain information in the supplemental package is shown pro forma for the consummation of pending transactions. The pro forma adjustments are based upon available information and assumptions that we believe are reasonable. There is no assurance that the pending transactions will occur. On the cover and page 2: Northpark Private Hospital, an acute care hospital in Australia operated by Healthscope. MEDICALPROPERTIESTRUST.COM Q1 2020 | SUPPLEMENTAL INFORMATION 2

Chairman, President and Chief Executive Officer Executive Vice President and Chief Financial Officer Executive Vice President, Chief Operating Officer and Secretary Vice President, Controller and Chief Accounting Officer Vice President, Managing Director of Asset Management and Underwriting Vice President, International Acquisitions Treasurer and Managing Director of Capital Markets Medical Properties Trust, Inc. is a self-advised real estate investment trust formed in 2003 to acquire and develop net-leased hospital facilities. From its inception in Birmingham, Alabama, the Company has grown to become one of the world’s largest owners of hospitals with 389 facilities and approximately 41,000 licensed beds in eight countries and across three continents. MPT’s financing model facilitates acquisitions and recapitalizations and allows operators of hospitals to unlock the value of their real estate assets to fund facility improvements, technology upgrades and other investments in operations. COMPANY OVERVIEW 3 OFFICERS Edward K. Aldag, Jr. R. Steven Hamner Emmett E. McLean J. Kevin Hanna Rosa H. Hooper R. Lucas Savage Charles R. Lambert BOARD OF DIRECTORS Edward K. Aldag, Jr. G. Steven Dawson R. Steven Hamner Caterina A. Mozingo Elizabeth N. Pitman D. Paul Sparks, Jr. Michael G. Stewart C. Reynolds Thompson, III CORPORATE HEADQUARTERS Medical Properties Trust, Inc. 1000 Urban Center Drive, Suite 501 Birmingham, AL 35242 (205) 969-3755 (205) 969-3756 (fax) www.medicalpropertiestrust.com Q1 2020 | SUPPLEMENTAL INFORMATION MPT Officers: Charles R. Lambert, Rosa H. Hooper, R. Lucas Savage, Edward K. Aldag, Jr., R. Steven Hamner, Emmett E. McLean and J. Kevin Hanna. MEDICALPROPERTIESTRUST.COM

INVESTOR RELATIONS Tim Berryman Director of Investor Relations (205) 397-8589 tberryman@medicalpropertiestrust.com COMPANY OVERVIEW (continued) CAPITAL MARKETS Charles Lambert Treasurer and Managing Director of Capital Markets (205) 397-8897 clambert@medicalpropertiestrust.com TRANSFER AGENT American Stock Transfer and Trust Company 6201 15th Avenue Brooklyn, NY 11219 STOCK EXCHANGE LISTING AND TRADING SYMBOL New York Stock Exchange (NYSE): MPW SENIOR UNSECURED DEBT RATINGS Moody’s – Ba1 Standard & Poor’s – BBBQ1 2020 | SUPPLEMENTAL INFORMATION 4 MEDICALPROPERTIESTRUST.COM Above: Clinique de Genolier, an acute care hospital in Switzerland owned by Infracore SA. MPT owns a minority interest in Infracore.

MEDICALPROPERTIESTRUST.COM FINANCIAL INFORMATION RECONCILIATION OF NET INCOME TO FUNDS FROM OPERATIONS (Unaudited) (Amounts in thousands, except per share data) March 31, 2020 March 31, 2019 FFO INFORMATION: Net income attributable to MPT common stockholders $ 8 0,992 $ 75,822 Participating securities’ share in earnings (464) ( 476) Net income, less participating securities’ share in earnings $ 8 0,528 $ 75,346 Depreciation and amortization 70,502 39,854 Gain on sale of real estate (1,325) - Real estate impairment charges 19,006 - Funds from operations $ 1 68,711 $ 115,200 Write-off of straight-line rent and other, net of tax 7 ,717 2,596 Non-cash fair value adjustments 1 4,195 - Unutilized financing fees 6 11 - Normalized funds from operations $ 1 91,234 $ - $ 117,796 Share-based compensation 10,036 6,715 Debt costs amortization 3,409 2,067 Straight-line rent revenue and other (49,614) (28,050) Adjusted funds from operations $ 1 55,065 $ 98,528 PER DILUTED SHARE DATA: Net income, less participating securities’ share in earnings $ 0.15 $ 0.20 Depreciation and amortization 0.13 0.10 Gain on sale of real estate - - Real estate impairment charges 0.04 - Funds from operations $ 0.32 $ 0.30 Write-off of straight-line rent and other, net of tax 0.02 0.01 Non-cash fair value adjustments 0.03 - Unutilized financing fees - - Normalized funds from operations $ 0.37 $ 0.31 Share-based compensation 0.02 0.02 Debt costs amortization - 0.01 Straight-line rent revenue and other (0.09) ( 0.08) Adjusted funds from operations $ 0.30 $ 0.26 For the Three Months Ended Notes: (A) Certain line items above (such as real estate depreciation) include our share of such income/expense from unconsolidated joint ventures. These amounts are included with the activity of all of our equity interests in the “Earnings from equity interests” line on the consolidated statements of income. (B) Investors and analysts following the real estate industry utilize funds from operations, or FFO, as a supplemental performance measure. FFO, reflecting the assumption that real estate asset values rise or fall with market conditions, principally adjusts for the effects of GAAP depreciation and amortization of real estate assets, which assumes that the value of real estate diminishes predictably over time. We compute FFO in accordance with the definition provided by the National Association of Real Estate Investment Trusts, or NAREIT, which represents net income (loss) (computed in accordance with GAAP), excluding gains (losses) on sales of real estate and impairment charges on real estate assets, plus real estate depreciation and amortization and after adjustments for unconsolidated partnerships and joint ventures. In addition to presenting FFO in accordance with the NAREIT definition, we also disclose normalized FFO, which adjusts FFO for items that relate to unanticipated or non-core events or activities or accounting changes that, if not noted, would make comparison to prior period results and market expectations less meaningful to investors and analysts. We believe that the use of FFO, combined with the required GAAP presentations, improves the understanding of our operating results among investors and the use of normalized FFO makes comparisons of our operating results with prior periods and other companies more meaningful. While FFO and normalized FFO are relevant and widely used supplemental measures of operating and financial performance of REITs, they should not be viewed as a substitute measure of our operating performance since the measures do not reflect either depreciation and amortization costs or the level of capital expenditures and leasing costs necessary to maintain the operating performance of our properties, which can be significant economic costs that could materially impact our results of operations. FFO and normalized FFO should not be considered an alternative to net income (loss) (computed in accordance with GAAP) as indicators of our results of operations or to cash flow from operating activities (computed in accordance with GAAP) as an indicator of our liquidity. We calculate adjusted funds from operations, or AFFO, by subtracting from or adding to normalized FFO (i) non-cash revenue, (ii) non-cash share-based compensation expense, and (iii) amortization of deferred financing costs. AFFO is an operating measurement that we use to analyze our results of operations based on the receipt, rather than the accrual, of our rental revenue and on certain other adjustments. We believe that this is an important measurement because our leases generally have significant contractual escalations of base rents and therefore result in recognition of rental income that is not collected until future periods, and costs that are deferred or are non-cash charges. Our calculation of AFFO may not be comparable to AFFO or similarly titled measures reported by other REITs. AFFO should not be considered as an alternative to net income (calculated pursuant to GAAP) as an indicator of our results of operations or to cash flow from operating activities (calculated pursuant to GAAP) as an indicator of our liquidity. Q1 2020 | SUPPLEMENTAL INFORMATION 5

MEDICALPROPERTIESTRUST.COM FINANCIAL INFORMATION DEBT SUMMARY (As of March 31, 2020) ($ amounts in thousands) Debt Instrument Rate Type Rate Balance 2021 Credit Facility Revolver Variable - $ - 2022 Term Loan Variable 2.460% 2 00,000 4.000% Notes Due 2022 (€500M) (B) Fixed 4.000% 5 51,550 2.550% Notes Due 2023 (£400M) (B) Fixed 2.550% 4 96,800 2024 AUD Term Loan (AUD$1.2B)(B) Fixed 2.450% 7 35,720 6.375% Notes Due 2024 Fixed 6.375% 5 00,000 5.500% Notes Due 2024 Fixed 5.500% 3 00,000 3.325% Notes Due 2025 (€500M) (B) Fixed 3.325% 5 51,550 2025 GBP Term Loan (£700M) (B) Fixed 1.949% 8 69,400 5.250% Notes Due 2026 Fixed 5.250% 5 00,000 5.000% Notes Due 2027 Fixed 5.000% 1 ,400,000 3.692% Notes Due 2028 (£600M) (B) Fixed 3.692% 7 45,200 4.625% Notes Due 2029 Fixed 4.625% 9 00,000 $ 7 ,750,220 Debt issuance costs and discount (65,927) Weighted average rate 3.958% $ 7 ,684,293 (A) We have a $1.3 billion unsecured revolving credit facility which matures in February 2021 and can be extended for an additional 12 months at our option. (B) Non-USD denominated debt converted to U.S. dollars at March 31, 2020. (C) We entered into an interest rate swap transaction, effective July 3, 2019, to fix the interest rate to 2.450% for the duration of the loan. (D) We entered into an interest rate swap transaction, effective March 6, 2020, to fix the interest rate to 1.949% for the duration of the loan. Rate Type as Percentage of Total Debt Fixed 97.4% Variable 2.6% (C) (D) (A) Q1 2020 | SUPPLEMENTAL INFORMATION 6

MEDICALPROPERTIESTRUST.COM FINANCIAL INFORMATION DEBT MATURITY SCHEDULE ($ amounts in thousands) Debt Instrument 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2021 Credit Facility Revolver $ - $ - $ - $ - $ - $ - $ - $ - $ - $ - 2022 Term Loan - - 200,000 - - - - - - - 4.000% Notes Due 2022 (€500M) (A) - - 551,550 - - - - - - - 2.550% Notes Due 2023 (£400M) (A) - - - 4 96,800 - - - - - - 2024 AUD Term Loan (AUD$1.2B)(A) - - - - 735,720 - - - - - 6.375% Notes Due 2024 - - - - 500,000 - - - - - 5.500% Notes Due 2024 - - - - 300,000 - - - - - 3.325% Notes Due 2025 (€500M) (A) - - - - - 551,550 - - - - 2025 GBP Term Loan (£700M) (A) - - - - - 869,400 - - - - 5.250% Notes Due 2026 - - - - - - 5 00,000 - - - 5.000% Notes Due 2027 - - - - - - - 1,400,000 - - 3.692% Notes Due 2028 (£600M) (A) - - - - - - - - 7 45,200 - 4.625% Notes Due 2029 - - - - - - - - - 9 00,000 $ - $ - $ 751,550 $ 4 96,800 $ 1,535,720 $ 1,420,950 $ 5 00,000 $ 1,400,000 $ 7 45,200 $ 9 00,000 (A) Non-USD denominated debt converted to U.S. dollars at March 31, 2020. $- $- $751,550 $496,800 $1,535,720 $1,420,950 $500,000 $1,400,000 $745,200 $900,000 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2022 Term Loan 4.000% Notes Due 2022 2.550% Notes Due 2023 2024 AUD Term Loan 6.375% Notes Due 2024 5.500% Notes Due 2024 3.325% Notes Due 2025 2025 GBP Term Loan 5.250% Notes Due 2026 5.000% Notes Due 2027 3.692% Notes Due 2028 4.625% Notes Due 2029 $1,200,000 $1,000,000 $800,000 $600,000 $400,000 $- $1,400,000 $1,600,000 $1,800,000 $200,000 Q1 2020 | SUPPLEMENTAL INFORMATION 7

MEDICALPROPERTIESTRUST.COM FINANCIAL INFORMATION PRO FORMA NET DEBT / ANNUALIZED ADJUSTED EBITDA (Unaudited) (Amounts in thousands) For the Three Months Ended March 31, 2020 Net income attributable to MPT common stockholders $ 80,992 Pro forma adjustments for acquisitions and other â½á´¬â¾ 11,712 Pro forma net income $ 92,704 Add back: Interest (B) 79,638 Depreciation and amortization (B) 69,928 Share-based compensation 10,036 Gain on sale of real estate (1,325) Impairment charges 19,006 Write-off of s traig ht-lin e rent an d other, net of tax 7,717 Non-cash fair value adjustments 14,195 Unutilized financing fees 611 Income tax (B) 4,517 1Q 2020 Pro forma adjusted EBITDA $ 297,027 Annualization $ 1,188,108 Total debt $ 7,684,293 Pro forma changes to net debt after March 31, 2020 (A) (674,201) Pro forma net debt $ 7,010,092 Pro forma net debt / annualized adjusted EBITDA 5.9x GAAP lease rate on the recent United Kingdom acquisition. Investors and analysts following the real estate industry utilize net debt (debt less cash) to EBITDA (net income before interest expense, income taxes, depreciation and amortization) as a measurement of leverage that shows how many years it would take for us to pay back our debt, assuming net debt and EBITDA are held constant. The table above considers the pro forma effects on net debt and EBITDA from investments and capital transactions that were either completed during the period or disclosed as firm commitments, assuming such transactions were consummated/fully funded as of the beginning of the period. In addition, we show EBITDA adjusted to exclude share-based compensation, gains or losses on real estate and other dispositions, debt refinancing or similar charges, and impairment or other non-cash charges to derive Pro forma Annualized Adjusted EBITDA, which is a non- GAAP measure. We believe Pro forma Net Debt and Pro forma Annualized Adjusted EBITDA are useful to investors and analysts as they allow for a more current view of our credit quality and allow for the comparison of our credit strength between periods and to other real estate companies without the effect of items that by their nature are not comparable from period to period. (B) Includes our share of interest, real estate depreciation and income tax expense from unconsolidated joint ventures. (A) Reflects full quarter impact of our mid-Q1 2020 investments, building improvements and disposals, as well as a new lease with a higher Q1 2020 | SUPPLEMENTAL INFORMATION 8

MEDICALPROPERTIESTRUST.COM PORTFOLIO INFORMATION LEASE AND LOAN MATURITY SCHEDULE (A) ($ amounts in thousands) Years of Maturities (B) Total Properties (C) Base Rent/Interest (D) Percentage of Total Base Rent/Interest 2020 - $ - - 2021 2 3,444 0.3% 2022 18 86,736 8.0% 2023 4 13,748 1.3% 2024 2 5,516 0.5% 2025 6 21,689 2.0% 2026 2 8,850 0.8% 2027 1 3,183 0.3% 2028 4 5,536 0.5% 2029 16 51,708 4.8% 2030 - - - Thereafter 309 885,845 81.5% 364 ### $ 1,086,255 100.0% (A) (B) (C) (D) Reflects all properties, including those that are part of joint ventures, except vacant properties representing less than 1.0% of total pro forma gross assets, and three facilities that are under development. Lease/Loan expiration is based on the fixed term of the lease/loan and does not factor in potential renewal options provided for in our agreements. Represents base rent/interest income on an annualized basis but does not include tenant recoveries, additional rents and other lease-related adjustments to revenue (i.e., straight-line rents and deferred revenues). Schedule includes leases and mortgage loans. 0.0% 0.3% 8.0% 1.3% 0.5% 2.0% 0.8% 0.3% 0.5% 4.8% 0.0% 81.5% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% Percentage of Total Base Q1 2020 | SUPPLEMENTAL INFORMATION 9

MEDICALPROPERTIESTRUST.COM PORTFOLIO INFORMATION TOTAL PRO FORMA GROSS ASSETS AND ACTUAL REVENUE BY ASSET TYPE (March 31, 2020) ($ amounts in thousands) Asset Types Total Gross Assets Percentage of Total Gross Assets 2020 Revenue Percentage of 2020 Revenue General Acute Care Hospitals $ 13,329,890 80.8% $ 269,461 84.6% Inpatient Rehabilitation Hospitals 1,748,467 10.6% 40,631 12.7% Long-Term Acute Care Hospitals 348,217 2.1% 8,575 2.7% Other 1,072,906 6.5% - - Total $ 16,499,480 100.0% $ 318,667 100.0% Domestic Pro Forma Gross Assets by Asset Type Total Pro Forma Gross Assets by Asset Type (A) Includes gross real estate assets, other loans, equity investments, and pro rata portion of gross assets in joint venture arrangements, assuming all binding real estate commitments on new investments and unfunded amounts on development deals and commenced capital improvement projects are fully funded. See press release dated April 29, 2020 for reconciliation of total assets to pro forma total gross assets at March 31, 2020. (B) Includes revenue from properties owned through joint venture arrangements. Domestic Actual Revenue by Asset Type Total Actual Revenue by Asset Type Pro Forma Actual 83% 6% 3% 8% General Acute Care Hospitals Inpatient Rehabilitation Hospitals Long-Term Acute Care Hospitals Other 88% 8% 4% 81% 11% 2% 6% General Acute Care Hospitals Inpatient Rehabilitation Hospitals Long-Term Acute Care Hospitals Other 84% 13% 3% (A) (B) Q1 2020 | SUPPLEMENTAL INFORMATION 10

MEDICALPROPERTIESTRUST.COM PORTFOLIO INFORMATION TOTAL PRO FORMA GROSS ASSETS AND ACTUAL REVENUE BY OPERATOR (March 31, 2020) ($ amounts in thousands) Operators Total Gross Assets Percentage of Total Gross Assets 2020 Revenue Percentage of 2020 Revenue Steward Health Care Massachusetts market $ 1 ,491,782 9.0% $ 3 4,615 10.9% Utah market 1 ,051,714 6.4% 2 1,781 6.8% Texas/Arkansas/Louisiana market 7 61,301 4.6% 1 8,046 5.7% Arizona market 3 32,239 2.0% 8 ,191 2.6% Ohio/Pennsylvania market 2 03,400 1.2% 5 ,000 1.6% Florida market 2 21,192 1.4% 3 ,626 1.1% Circle Health 2 ,143,720 13.0% 3 2,342 10.1% Prospect Medical Holdings 1 ,569,594 9.5% 3 7,916 11.9% LifePoint Health 1 ,202,435 7.3% 2 6,594 8.3% Prime Healthcare 1 ,144,736 6.9% 3 2,162 10.1% 36 operators 5 ,304,461 32.2% 9 8,394 30.9% Other 1 ,072,906 6.5% - - Total $ 1 6,499,480 100.0% $ 3 18,667 100.0% (A) Includes gross real estate assets, other loans, equity investments, and pro rata portion of gross assets in joint venture arrangements, assuming all binding real estate commitments on new investments and unfunded amounts on development deals and commenced capital improvement projects are fully funded. See press release dated April 29, 2020 for reconciliation of total assets to pro forma total gross assets at March 31, 2020. (B) Includes revenue from properties owned through joint venture arrangements. Note: No single facility accounts for more than 2.3% of total pro forma gross assets. Total Pro Forma Gross Assets by Operator Total Actual Revenue by Operator Pro Forma Actual

MEDICALPROPERTIESTRUST.COM TOTAL PRO FORMA GROSS ASSETS AND ACTUAL REVENUE BY U.S. STATE AND COUNTRY (March 31, 2020) ($ amounts in thousands) U.S. States and Other Countries Total Gross Assets Percentage of Total Gross Assets 2020 Revenue Percentage of 2020 Revenue Massachusetts $ 1,497,182 9.1% $ 34,773 10.9% Texas 1,388,695 8.4% 26,431 8.3% California 1,299,747 7.9% 34,946 11.0% Utah 1,086,695 6.6% 22,748 7.1% Pennsylvania 9 07,969 5.5% 21,669 6.8% 29 Other States 4,009,418 24.3% 92,766 29.1% Other 8 47,377 5.1% - - United States $ 11,037,083 66.9% $ 233,333 73.2% United Kingdom $ 2,578,626 15.6% $ 38,875 12.2% Germany 1,095,076 6.6% 23,804 7.5% Australia 7 84,093 4.8% 13,006 4.1% Switzerland 4 98,228 3.0% 5,913 1.9% Spain 1 55,995 0.9% 1,374 0.4% 2 Other Countries 1 24,850 0.8% 2,362 0.7% Other 2 25,529 1.4% - - International $ 5,462,397 33.1% $ 85,334 26.8% Total $ 16,499,480 100.0% $ 318,667 100.0% (A) Includes gross real estate assets, other loans, equity investments, and pro rata portion of gross assets in joint venture arrangements, assuming all binding real estate commitments on new investments and unfunded amounts on development deals and commenced capital improvement projects are fully funded. See press release dated April 29, 2020 for reconciliation of total assets to pro forma total gross assets at March 31, 2020. (B) Includes revenue from properties owned through joint venture arrangements. PORTFOLIO INFORMATION Pro Forma Actual 67% 16% 7% 5% 3%

MEDICALPROPERTIESTRUST.COM PORTFOLIO INFORMATION SAME STORE EBITDARM(A) RENT COVERAGE YOY and Sequential Quarter Comparisons by Property Type Stratification of Portfolio EBITDARM Rent Coverage EBITDARM Rent Coverage TTM Investment (in thousands) No. of Facilities Percentage of Investment Greater than or equal to 4.50x $ 32,642 2 0.5% 3.00x - 4.49x $ 121,774 2 1.7% 1.50x - 2.99x $ 82,604 6 1.1% Less than 1.50x $ 7,997 2 0.1% Total Master Leased, Cross-Defaulted and/or with Parent Guaranty: 2.6x $ 6,972,860 174 96.6% General Acute Care Hospitals Master Leased, Cross- Defaulted and/or with Parent Guaranty: 2.9x $ 5,347,483 68 74.1% Inpatient Rehabilitation Facilities Master Leased, Cross- Defaulted and/or with Parent Guaranty: 2.1x $ 1,403,129 94 19.4% Long-Term Acute Care Hospitals Master Leased, Cross- Defaulted and/or with Parent Guaranty: 1.9x $ 222,248 12 3.1% Notes: Same Store represents properties with at least 24 months of financial reporting data. Properties that do not provide financial reporting and disposed assets are not included. All data presented is on a trailing twelve month basis. (A) EBITDARM adjusted for non-recurring items. 3.0x 2.0x 1.6x 2.7x 2.9x 2.1x 1.9x 2.7x 3.0x 2.0x 1.8x 2.7x 2.9x 2.1x 1.9x 2.7x 0.00x 1.00x 2.00x 3.00x 4.00x 5.00x General Acute Care Hospitals Inpatient Rehabilitation Facilities Long-Term Acute Care Hospitals Total Portfolio Q4 2018 (YoY) Q4 2019 (YoY) Q3 2019 (QoQ) Q4 2019 (QoQ) 0.5% 1.7% 1.1%0.1% 74.1% 19.4% 3.1% Greater than or equal to 4.50x 3.00x - 4.49x 1.50x - 2.99x Less than 1.50x General Acute Master Lease, Cross-Default or Parent Guaranty Rehab Master Lease, Cross-Default or Parent Guaranty LTACH Master Lease, Cross-Default or Parent Guaranty Q1 2020 | SUPPLEMENTAL INFORMATION 13

MEDICALPROPERTIESTRUST.COM SUMMARY OF COMPLETED ACQUISITIONS / DEVELOPMENT PROJECTS FOR THE THREE MONTHS ENDED MARCH 31, 2020 (Amounts in thousands) Operator Location Investment (A) Rent Commencement Date Acquisition/ Development Circle Health United Kingdom $ 1,973,272 1/8/2020 Acquisition Surgery Partners Idaho 108,856 1/21/2020 Development $ 2,082,128 SUMMARY OF CURRENT DEVELOPMENT PROJECTS AS OF MARCH 31, 2020 (Amounts in thousands) Operator Location Commitment Costs Incurred as of 3/31/2020 Estimated Rent Commencement Date Circle Health United Kingdom $ 44,531 $ 41,207 Q3 2020 Circle Health Rehabilitation United Kingdom 20,074 17,097 Q3 2020 NeuroPsychiatric Hospitals Texas 27,500 13,169 Q4 2020 $ 92,105 $ 71,473 (A) Excludes transaction costs, including real estate transfer and other taxes and accounts for the exchange rate as of the acquisition date. (B) Represents £35.9 million commitment converted to USD at March 31, 2020. (C) Represents £16.2 million commitment converted to USD at March 31, 2020. PORTFOLIO INFORMATION (B) (C) Q1 2020 | SUPPLEMENTAL INFORMATION 14

MEDICALPROPERTIESTRUST.COM MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES Consolidated Statements of Income (Unaudited) (Amounts in thousands, except per share data) March 31, 2020 March 31, 2019 REVENUES Rent billed $ 171,767 $ 108,598 Straight-line rent 31,421 20,651 Income from financing leases 52,436 17,280 Interest and other income 38,508 33,925 Total revenues 294,132 180,454 EXPENSES Interest 80,899 50,551 Real estate depreciation and amortization 60,921 33,352 Property-related 5,572 3,066 General and administrative 33,385 23,451 Total expenses 180,777 110,420 OTHER INCOME (EXPENSE) Gain on sale of real estate 1,325 - Real estate impairment charges ( 19,006) - Earnings from equity interests 4,079 3,720 Unutilized financing fees ( 611) - Other (including mark-to-market adjustments on equity securities) ( 13,975) 204 Total other (expense) income ( 28,188) 3,924 Income before income tax 8 5,167 73,958 Income tax (expense) benefit ( 4,010) 2,333 Net income 81,157 76,291 Net income attributable to non-controlling interests ( 165) ( 469) Net income attributable to MPT common stockholders $ 80,992 $ 75,822 EARNINGS PER COMMON SHARE - BASIC AND DILUTED Net income attributable to MPT common stockholders $ 0.15 $ 0.20 WEIGHTED AVERAGE SHARES OUTSTANDING - BASIC 521,076 380,551 WEIGHTED AVERAGE SHARES OUTSTANDING - DILUTED 522,179 381,675 $ - DIVIDENDS DECLARED PER COMMON SHARE $ 0.27 $ 0.25 For the Three Months Ended FINANCIAL STATEMENTS Q1 2020 | SUPPLEMENTAL INFORMATION 15

MEDICALPROPERTIESTRUST.COM MEDICAL PROPERTIES TRUST, INC. AND SUBSIDIARIES Consolidated Balance Sheets (Amounts in thousands, except per share data) March 31, 2020 December 31, 2019 (Unaudited) (A) ASSETS Real estate assets Land, buildings and improvements, intangible lease assets, and other $ 9,933,444 $ 8,102,754 Investment in financing leases 2,068,166 2,060,302 Mortgage loans 1,275,543 1,275,022 Gross investment in real estate assets 13,277,153 11,438,078 Accumulated depreciation and amortization ( 627,467) ( 570,042) Net investment in real estate assets 12,649,686 10,868,036 Cash and cash equivalents 500,213 1,462,286 Interest and rent receivables 38,768 3 1,357 Straight-line rent receivables 355,424 3 34,231 Equity investments 834,430 9 26,990 Other loans 546,691 5 44,832 Other assets 312,875 2 99,599 Total Assets $ 15,238,087 $ 14,467,331 LIABILITIES AND EQUITY Liabilities Debt, net $ 7,684,293 $ 7,023,679 Accounts payable and accrued expenses 428,136 2 91,489 Deferred revenue 24,001 1 6,098 Obligations to tenants and other lease liabilities 119,147 1 07,911 Total Liabilities 8,255,577 7,439,177 Equity Preferred stock, $0.001 par value. Authorized 10,000 shares; no shares outstanding - - Common stock, $0.001 par value. Authorized 750,000 shares; issued and outstanding - 522,435 shares at March 31, 2020 and 517,522 shares at December 31, 2019 5 22 5 18 Additional paid-in capital 7,079,913 7,008,199 Retained earnings 14,025 8 3,012 Accumulated other comprehensive loss ( 111,280) (62,905) Treasury shares, at cost ( 777) (777) Total Medical Properties Trust, Inc. Stockholders’ Equity 6,982,403 7,028,047 Non-controlling interests 1 07 1 07 Total Equity 6,982,510 7,028,154 Total Liabilities and Equity $ 15,238,087 $ 14,467,331 (A) Financials have been derived from the prior year audited financial statements. FINANCIAL STATEMENTS Q1 2020 | SUPPLEMENTAL INFORMATION 16

MEDICALPROPERTIESTRUST.COM FINANCIAL STATEMENTS UNCONSOLIDATED JOINT VENTURE INVESTMENTS (As of and for the three months ended March 31, 2020) (Unaudited) ($ amounts in thousands) Real Estate Joint Venture Details Total revenues $ 51,793 Expenses: Interest 14,442 Real estate depreciation and amortization 20,261 General and administrative 1,400 Other 2,676 Income taxes 3,930 Total expenses 42,709 Net income $ 9,084 Total Assets $ 3,892,201 Debt, (third party) $ 1,144,834 Shareholder loans 665,196 Other liabilities 383,724 Total Liabilities $ 2,193,754 Debt to EBITDA (annualized) 6.0x Debt to Total Assets 29.4% Joint Venture Impact Income Statement Impact to MPT Amounts Real estate joint venture income(1) $ 4 ,079 Earnings from equity interests Management fee revenue $ 1 40 Interest and other income Shareholder loan interest revenue $ 4 ,223 Interest and other income Balance Sheet Impact to MPT Amounts Real estate joint venture investments $ 6 18,670 Equity investments Other joint venture investments 2 15,760 Equity investments Total joint venture investments $ 8 34,430 Shareholder loans $ 3 30,672 Other loans (1) Includes $1.5 million of straight-line rent revenue and $9.5 million of depreciation and amortization expense. Financial Statement Location Financial Statement Location Income Statement Balance Sheet Information Leverage Metrics (Third-party debt only) Q1 2020 | SUPPLEMENTAL INFORMATION 17

1000 Urban Center Drive, Suite 501 Birmingham, AL 35242 (205) 969-3755 NYSE: MPW www.medicalpropertiestrust.com At the Very Heart of Healthcare.® Contact: Tim Berryman, Director of Investor Relations (205) 397-8589 or tberryman@medicalpropertiestrust.com or Charles Lambert, Treasurer and Managing Director of Capital Markets (205) 397-8897 or clambert@medicalpropertiestrust.com Medical Properties Trust